TiPs collects predicted drug targets in 150 pathogen species. The structural details of the drug mode of binding are also provided. Predictions are made using the information coming from drug-target three-dimensional complexes and by exploting the homology relationships of known drug targets with pathogen proteins. Predicted pathogen targets are further annotated with sequence, structural and functional information.

Users can quickly prioritise drug-target pairs by running simple queries, getting a list of candidate drug targets, and analysing predicted drug mechanism of action.

Search drug-target pairs using one or more of the following criteria
e.g. Leishmania major (or type * for any)
e.g. Leishmania

Filter by (optional): ?
or by selecting a protein of interest (Uniprot Id)
e.g. G4VP62

Sapienza University of Rome
King Abdullah University of Science and Technology
Fondazione Roma
TiPs - March 2013 ©