TiPs collects predicted drug targets in 150 pathogen species. The structural details of the drug mode of binding are also provided. Predictions are made using the information coming from drug-target three-dimensional complexes and by exploting the homology relationships of known drug targets with pathogen proteins. Predicted pathogen targets are further annotated with sequence, structural and functional information.
Users can quickly prioritise drug-target pairs by running simple queries, getting a list of candidate drug targets, and analysing predicted drug mechanism of action.