PIGS: Automatic prediction of immunoglobulin structures
Marcatili P., Tramontano A.
University of Rome "Sapienza"
The new version of PIGS is now available: PIGSPro
) is a web server for the automatic modeling of immunoglobulin variable domains based on the canonical structure method.
It has a user-friendly and flexible interface, that allows the user to choose templates (for the frameworks and the loops) and modeling strategies in an automatic or manual fashion. Its final output is a complete three-dimensional model of the target antibody that can be downloaded or displayed on-line. The server is freely accessible to academic users, with no restriction on the number of submitted sequences.
If you use this web server, please cite the following reference:
Marcatili P, Rosi A, Tramontano A.,PIGS: automatic prediction of antibody structures. Bioinformatics. 2008 Sep 1;24(17):1953-4. Epub 2008 Jul 19.