Picmi is a server which can map:
– nucleotide point variations (Nucleotide Input)
on the genome, reporting in which region they are located and, when they fall in a coding exon, classifying the mutations as missense, synonymous, nonsense.
– amino acid point variations (Amino acid Input)
of a Swiss-Prot protein sequence. The system infers, whenever this can be done unambiguously, the corresponding nucleotide variations, that are subsequently analysed as described above.
NOTE: the pipeline, the input and output formats and all the options are thoroughly described in the help page